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Article

MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults.

Nutrition journal - 10 Jan 2012

Qin Xianhui, Li Jianping, Cui Yimin, Liu Zeyuan, Zhao Zhigang, Ge Junbo, Guan Deming, Hu Jian, Wang Yanni, Zhang Fumin, Xu Xin, Wang Xiaobin, Xu Xiping, Huo Yong

Abstract excerpt

BACKGROUND: This study aimed to investigate if the homocysteine-lowering efficacy of two commonly used physiological doses (0.4 mg/d and 0.8 mg/d) of folic acid (FA) can be modified by individual methylenetetrahydrofolate reductase (MTHFR) C677T and/or methionine synthase (MTR) A2756G polymorphisms in hypertensive Chinese adults. METHODS: A total of 480 subjects with mild or moderate essential hypertension were...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
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Source

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Identifiers

PMID: 22230384
DOI: 10.1186/1475-2891-11-2
PMCID: PMC3274435

Genes

MTHFR
MTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults.PMID 22230384Read ↗

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