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Article

BH3 profiling--measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions.

Cancer letters - 28 May 2013

Del Gaizo Moore Victoria, Letai Anthony

Abstract excerpt

Apoptosis is a form of programmed cell death that is controlled at the mitochondrion by the BCL-2 family of proteins. While much has been learned about the structure and function of these proteins over the past two decades, the important goal of predicting cell fate decisions in response to toxic stimuli is largely unrealized. BH3 profiling is a functional approach that can be used to predict cellular responses...

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Identifiers

PMID: 22230093
DOI: 10.1016/j.canlet.2011.12.021
PMCID: PMC3770266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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