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Article

Effect of acute ethanol drinking on alcohol metabolism in subjects with different ADH and ALDH genotypes.

Alcohol (Fayetteville, N.Y.) - 1 Jan 2000

Meier-Tackmann D, Leonhardt R A, Agarwal D P, Goedde H W

Abstract excerpt

The effect of different amounts of orally ingested ethanol on plasma alcohol dehydrogenase (ADH) and erythrocyte aldehyde dehydrogenase (ALDH), as well as on the blood ethanol and acetaldehyde levels, was examined in healthy nonalcoholic subjects. The genotypes at ADH2 and ALDH2 locus were identified in enzymatically amplified blood DNA by hybridization with allele-specific oligonucleotides. While the Japanese...

Topics

Acetaldehyde
Adult
Alcohol Dehydrogenase
Alcohol Drinking
Aldehyde Dehydrogenase
Alleles
Asian People
Ethanol
Female
Genotype
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

White People

Source

Identifiers

PMID: 2222844
DOI: 10.1016/0741-8329(90)90025-8

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2222844-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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