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Article

Influence of cytochrome 2C19 allelic variants on on-treatment platelet reactivity evaluated by five different platelet function tests.

Thrombosis research - 1 May 2012

Gremmel Thomas, Kopp Christoph W, Moertl Deddo, Seidinger Daniela, Koppensteiner Renate, Panzer Simon, Mannhalter Christine, Steiner Sabine

Abstract excerpt

BACKGROUND: The antiplatelet effect of clopidogrel has been linked to cytochrome P450 2C19 (CYP2C19) carrier status. The presence of loss of function and gain of function variants were found to have a gene-dose effect on clopidogrel metabolism. However, genotyping is only one aspect of predicting response to clopidogrel and several platelet function tests are available to measure platelet response. Patients and...

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Source

Identifiers

PMID: 22154242
DOI: 10.1016/j.thromres.2011.11.019

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VASP
LTA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Influence of cytochrome 2C19 allelic variants on on-treatment platelet reactivity evaluated by five different platelet function tests.PMID 22154242Read ↗

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