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Article

A non-covalent interaction between small ubiquitin-like modifier-1 and Zac1 regulates Zac1 cellular functions.

The international journal of biochemistry & cell biology - 1 Mar 2012

Liu Shu-Ting, Chang Yung-Lung, Wang Wei-Ming, Chung Min-Huey, Lin Wei-Shiang, Chou Wei-Yuan, Huang Shih-Ming

Abstract excerpt

Zac1, a zinc-finger protein that regulates apoptosis and cell cycle arrest 1, such as p53, can induce cell-cycle arrest and apoptosis. The transactivation and coactivation functions of Zac1 may occur at non-promyelocytic leukemia nuclear body (PML-NB) sites in the presence of other PML-NB components, including ubiquitin-conjugating 9 (Ubc9). It is unclear whether post-translational modification of Zac1 by the...

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Identifiers

PMID: 22227369
DOI: 10.1016/j.biocel.2011.12.012

Genes

PML

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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