Article
Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1.
Biochemical and biophysical research communications - 22 Oct 1999
Mitsui K, Matsumoto A, Ohtsuka S, Ohtsubo M, Yoshimura A
Abstract excerpt
p21(Cip1/Waf1) inhibits cell-cycle progression by binding to G1 cyclin/CDK complexes and proliferating cell nuclear antigen (PCNA) through its N- and C-terminal domains, respectively. Here, we report a novel p21(Cip1/Waf1)-interacting protein, Ciz1 (for Cip1 interacting zinc finger protein), which contains polyglutamine repeats and glutamine-rich region in the N-terminus as well as three zinc-finger motifs and...
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