Article
Human leukocyte antigen variation and Parkinson's disease.
Parkinsonism & related disorders - 1 Jun 2011
Puschmann Andreas, Verbeeck Christophe, Heckman Michael G, Soto-Ortolaza Alexandra I, Lynch Timothy, Jasinska-Myga Barbara, Opala Grzegorz, Krygowska-Wajs Anna, Barcikowska Maria, Uitti Ryan J, Wszolek Zbigniew K, Ross Owen A
Abstract excerpt
A role for the immune system in the pathogenesis of Parkinson's Disease (PD) has previously been suggested. A recent genome-wide association (GWA) study identified an association between one single nucleotide polymorphism (SNP) in the human leucocyte antigen (HLA) region (HLA-DRA rs3129882) and PD in a population of American patients with European ancestry. In that study, the minor rs3129882 allele (G) was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
