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Article

Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner.

Pflugers Archiv : European journal of physiology - 1 Apr 2012

Komatsu Tomoko, Uchida Kunitoshi, Fujita Fumitaka, Zhou Yiming, Tominaga Makoto

Abstract excerpt

Transient receptor potential ankyrin 1 (TRPA1) is a calcium-permeable non-selective cation channel that is mainly expressed in primary nociceptive neurons. TRPA1 is activated by a variety of noxious stimuli, including cold temperatures, pungent compounds such as mustard oil and cinnamaldehyde, an...

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Source

Identifiers

PMID: 22222967
DOI: 10.1007/s00424-011-1069-4

Genes

TRPA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22222967-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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