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Article

Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network.

Developmental biology - 1 Mar 2012

Schaub Madeline, Nussbaum Justin, Verkade Heather, Ober Elke A, Stainier Didier Y R, Sakaguchi Takuya F

Abstract excerpt

Biliary epithelial cells line the intrahepatic biliary network, a complex three-dimensional network of conduits. The loss of differentiated biliary epithelial cells is the primary cause of many congenital liver diseases. We identified a zebrafish snapc4 (small nuclear RNA-activating complex polypeptide 4) mutant in which biliary epithelial cells initially differentiate but subsequently disappear. In these snapc4...

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Identifiers

PMID: 22222761
DOI: 10.1016/j.ydbio.2011.12.025
PMCID: PMC3711868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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