Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia

22 Apr 2017

Abstract excerpt

The gallbladder excretes cytotoxic bile acids into the duodenum through the cystic duct and common bile duct system. Sox17 haploinsufficiency causes biliary atresia-like phenotypes and hepatitis in late organogenesis mouse embryos, but the molecular and cellular mechanisms underlying this remain unclear. In this study, transcriptomic analyses revealed the early onset of cholecystitis in Sox17+/− embryos, together...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital Anomalies and Fetal Surgery
Share to Infant Nutrition and Health
Share to Pediatric Hepatobiliary Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28432216
DOI: 10.1242/dev.147512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresiaPMID 28432216Read ↗

Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladderSemantic proximity Read ↗

sox9b Is a Key Regulator of Pancreaticobiliary Ductal System DevelopmentSemantic proximity Read ↗

Wnt signaling in biliary development, proliferation, and fibrosisSemantic proximity Read ↗

Development of the Intrahepatic and Extrahepatic Biliary Tract: A Framework for Understanding Congenital DiseasesSemantic proximity Read ↗

Genetic contributors and modifiers of biliary atresia.Semantic proximity Read ↗

Core Hippo pathway components act as a brake on Yap and Taz in the development and maintenance of the biliary network.Semantic proximity Read ↗

Sox9 Is a Modifier of the Liver Disease Severity in a Mouse Model of Alagille SyndromeSemantic proximity Read ↗

Unraveling the pathogenesis and etiology of biliary atresia.Semantic proximity Read ↗

Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signalingSemantic proximity Read ↗

Role of YAP1 Signaling in Biliary Development, Repair, and DiseaseSemantic proximity Read ↗

Molecular phenotypes in early gallbladder and liver disease in the CFTR-/- sheep highlight aspects of cystic fibrosis-relevant hepatobiliary disease.Semantic proximity Read ↗

Genome-wide association studies in biliary atresia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.