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Article

EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking.

Molecular biology of the cell - 1 Feb 2012

Hokanson David E, Bretscher Anthony P

Abstract excerpt

Cell function requires the integration of cytoskeletal organization and membrane trafficking. Small GTP-binding proteins are key regulators of these processes. We find that EPI64, an apical microvillar protein with a Tre-2/Bub2/Cdc16 (TBC) domain that stabilizes active Arf6 and has RabGAP activity, regulates Arf6-dependent membrane trafficking. Expression of EPI64 in HeLa cells induces the accumulation of...

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Identifiers

PMID: 22219378
DOI: 10.1091/mbc.E11-06-0521
PMCID: PMC3279397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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