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In Vivo Tracking of Human Neural Stem Cells with 19F Magnetic Resonance Imaging

28 Dec 2011

Abstract excerpt

BACKGROUND: Magnetic resonance imaging (MRI) is a promising tool for monitoring stem cell-based therapy. Conventionally, cells loaded with ironoxide nanoparticles appear hypointense on MR images. However, the contrast generated by ironoxide labeled cells is neither specific due to ambiguous background nor quantitative. A strategy to overcome these drawbacks is (19)F MRI of cells labeled with perfluorocarbons. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22216163
DOI: 10.1371/journal.pone.0029040

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