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Differentiation of genetically modified canine bone mesenchymal stem cells labeled with superparamagnetic iron oxide into neural‑like cells.

Molecular medicine reports - 1 Jun 2018

Liu Xing-Long, Zu Qing-Quan, Wang Bin, Lu Shan-Shan, Xu Xiao-Quan, Liu Sheng, Shi Hai-Bin

Abstract excerpt

The use of mesenchymal stem cells (MSCs) has been reported to improve outcomes in various types of nervous system diseases, primarily based on their neural regenerative differentiation ability and paracrine effect on different neuroprotective cytokines. Genetically modified MSCs may enhance the paracrine effect and may further improve the cell‑based therapeutic outcome of nervous system diseases. Magnetic...

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PMID: 29620288
DOI: 10.3892/mmr.2018.8847

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BDNF

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