Article
In vivo MRI of intraspinally injected SPIO-labelled human CD34+ cells in a transgenic mouse model of ALS.
In vivo (Athens, Greece) - 1 Jan 2000
Willenbrock S, Knippenberg S, Meier M, Hass R, Wefstaedt P, Nolte I, Murua Escobar H, Petri S
Abstract excerpt
BACKGROUND/AIM: Administration of stem cells is a promising novel approach for treatment of neurodegenerative diseases. For in vivo monitoring of transplanted cells, non-invasive imaging modalities are needed. In this study we determined the tracking efficiency of a superparamagnetic iron oxide (SPIO)-labelled canine cell line (MTH53A) in vitro as well as the human CD34(+) umbilical cord blood stem cells (hUCBCs)...
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