Article
In vivo tracking of mesenchymal stem cells labeled with a novel chitosan-coated superparamagnetic iron oxide nanoparticles using 3.0T MRI.
Journal of Korean medical science - 1 Feb 2010
Reddy Alavala Matta, Kwak Byung Kook, Shim Hyung Jin, Ahn Chiyoung, Lee Hyo Sook, Suh Yong Jae, Park Eon Sub
Abstract excerpt
This study aimed to characterize and MRI track the mesenchymal stem cells labeled with chitosan-coated superparamagnetic iron oxide (Chitosan-SPIO). Chitosan-SPIO was synthesized from a mixture of FeCl(2) and FeCl(3). The human bone marrow derived mesenchymal stem cells (hBM-MSC) were labeled with 50 microg Fe/mL chitosan-SPIO and Resovist. The labeling efficiency was assessed by iron content, Prussian blue...
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