Article
Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles.
Nanoscale - 7 Aug 2014
Liu Jing, Wang Liqin, Cao Jianbo, Huang Yue, Lin Yu, Wu Xiaoyun, Wang Zhiyong, Zhang Fan, Xu Xiuqin, Liu Gang
Abstract excerpt
Stem cell based therapies offer significant potential in the field of regenerative medicine. The development of superparamagnetic iron oxide (SPIO) nanoparticle labeling and magnetic resonance imaging (MRI) have been increasingly used to track the transplanted cells, enabling in vivo determination of cell fate. However, the impact of SPIO-labeling on the cell phenotype and differentiation capacity of embryonic...
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