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Article

Zebrafish prox1b mutants develop a lymphatic vasculature, and prox1b does not specifically mark lymphatic endothelial cells.

PloS one - 1 Jan 2011

Tao Shijie, Witte Merlijn, Bryson-Richardson Robert J, Currie Peter D, Hogan Benjamin M, Schulte-Merker Stefan

Abstract excerpt

BACKGROUND: The expression of the Prospero homeodomain transcription factor (Prox1) in a subset of cardinal venous cells specifies the lymphatic lineage in mice. Prox1 is also indispensible for the maintenance of lymphatic cell fate, and is therefore considered a master control gene for lymphangiogenesis in mammals. In zebrafish, there are two prox1 paralogues, the previously described prox1 (also known as...

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Identifiers

PMID: 22216143
DOI: 10.1371/journal.pone.0028934
PMCID: PMC3247213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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