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Article

Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jul 2010

Roy Alec, Gorodetsky Elena, Yuan Qiaoping, Goldman David, Enoch Mary-Anne

Abstract excerpt

Childhood trauma is associated with hypothalamic-pituitary-adrenal (HPA) axis dysregulation and is a known risk factor for suicidal behavior. In this study we sought to determine whether the impact of childhood trauma on suicide risk might be modified by FKBP5, an HPA-axis regulating gene. Sixtee...

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Source

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Identifiers

PMID: 20090668
DOI: 10.1038/npp.2009.236
PMCID: PMC2962602

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20090668-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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