Article
Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas.
International journal of cancer - 1 Sept 2012
Scholtysik René, Nagel Inga, Kreuz Markus, Vater Inga, Giefing Maciej, Schwaenen Carsten, Wessendorf Swen, Trümper Lorenz, Loeffler Markus, Siebert Reiner, Küppers Ralf
Abstract excerpt
A single nucleotide polymorphism-chip analysis of 98 cases of aggressive B-cell lymphomas revealed a recurrent deletion at 19p13 in nine of the cases. Six further cases with deletions encompassing this region were found in array-comparative genomic hybridization data of 295 aggressive B-cell lymphomas from a previous study. Three cases even showed a homozygous deletion, suggesting a tumor suppressor gene in the...
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