Article
Establishment of the genomic structure and identification of thirteen single-nucleotide polymorphisms in the human RECK gene.
Cytogenetic and genome research - 1 Jan 2002
Eisenberg I, Hochner H, Sadeh M, Argov Z, Mitrani-Rosenbaum S
Abstract excerpt
The human RECK gene, mapped at 9p13-->p12, is known as a tumor suppressor gene and as a key regulator of extracellular matrix integrity and angiogenesis. We have established the entire genomic structure of this gene, which spans more than 87 kb and consists of 21 exons and 20 introns, and identified thirteen single nucleotide polymorphisms (SNPs). Four SNPs were identified in the coding region of the gene (exons...
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