Article
Recent genetic discoveries in osteoporosis, sarcopenia and obesity.
Endocrine journal - 1 Jan 2015
Urano Tomohiko, Inoue Satoshi
Abstract excerpt
Osteoporosis is a skeletal disorder characterized by low bone mineral density (BMD) and an increased susceptibility to fractures. Evidence from genetic studies indicates that BMD, a complex quantitative trait with a normal distribution, is genetically controlled. Genome-wide association studies (GWAS) as well as studies using candidate gene approaches have identified single-nucleotide polymorphisms (SNPs) that...
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