Article
KRAS mutation is associated with elevated myeloblastin activity in human lung adenocarcinoma.
Cancer genomics & proteomics - 1 Jan 2012
Wiedl Thomas, Collaud Stéphane, Hillinger Sven, Arni Stephan, Burgess Chris, Kroll Werner, Schraml Peter, Soltermann Alex, Moch Holger, Weder Walter
Abstract excerpt
Lung cancer is the leading cause of all cancer deaths worldwide with suboptimal prognosis and treatment options. Therefore this study aimed to identify molecular characteristics with a predictive clinical utility which at the same time might represent novel therapeutic targets for human lung adenocarcinoma. Within this study mutations of v-Ki-RAS2 Kirsten rat sarcoma viral oncogene homolog (KRAS), a gene...
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