Article
Evaluation of susceptibility locus for response to interferon-α based therapy in chronic hepatitis B patients in Chinese.
Antiviral research - 1 Feb 2012
Wu Xiaopan, Xin Zhenhui, Zhu Xilin, Pan Liping, Li Zhuo, Li Hui, Liu Ying
Abstract excerpt
In 2009, three independent genome-wide association studies reported that genetic variation in the interleukin 28B gene to be associated with the response to interferon-α/ribavirin therapy in hepatitis C virus genotype 1 infected patients. We carried out the present study to assess whether such polymorphisms also affect the therapy effect of another interferon-α responsive illness as chronic hepatitis B. Five...
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