Article
A case control association study and cognitive function analysis of neuropilin and tolloid-like 1 gene and schizophrenia in the Japanese population.
PloS one - 1 Jan 2011
Banno Masahiro, Koide Takayoshi, Aleksic Branko, Yamada Kazuo, Kikuchi Tsutomu, Kohmura Kunihiro, Adachi Yasunori, Kawano Naoko, Kushima Itaru, Ikeda Masashi, Inada Toshiya, Yoshikawa Takeo, Iwata Nakao, Ozaki Norio
Abstract excerpt
BACKGROUND: Using a knock-out mouse model, it was shown that NETO1 is a critical component of the NMDAR complex, and that loss of Neto1 leads to impaired hippocampal long term potentiation and hippocampal-dependent learning and memory. Moreover, hemizygosity of NETO1 was shown to be associated with autistic-like behavior in humans. PURPOSE OF THE RESEARCH: We examined the association between schizophrenia and the...
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