Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nogo Receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches.

PloS one - 28 Nov 2007

Hsu Ruby, Woodroffe Abigail, Lai Wen-Sung, Cook Melloni N, Mukai Jun, Dunning Jonathan P, Swanson Douglas J, Roos J Louw, Abecasis Gonçalo R, Karayiorgou Maria, Gogos Joseph A

Abstract excerpt

BACKGROUND: NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene. METHODOLOGY/PRINCIPAL FINDINGS: We evaluate evidence for genetic association between common RTN4R polymorphisms and schizophrenia in a large family sample of Afrikaner origin and screen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Behavior, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GPI-Linked Proteins

Share to Mice, Knockout

Share to Myelin Proteins

Share to Receptors, Cell Surface

Share to Schizophrenia

Share to Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 18043741
DOI: 10.1371/journal.pone.0001234
PMCID: PMC2077930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nogo Receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches.PMID 18043741Read ↗

Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth.Semantic proximity Read ↗

Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia ModelSemantic proximity Read ↗

No association between the genetic polymorphisms in the RTN4R gene and schizophrenia in the Chinese population.Semantic proximity Read ↗

A case control association study and cognitive function analysis of neuropilin and tolloid-like 1 gene and schizophrenia in the Japanese population.Semantic proximity Read ↗

Neuregulin 1 and susceptibility to schizophrenia.Semantic proximity Read ↗

Mutant mouse models: genotype-phenotype relationships to negative symptoms in schizophrenia.Semantic proximity Read ↗

Mutant models for genes associated with schizophrenia.Semantic proximity Read ↗

Neuregulin-1 and schizophrenia in the genome-wide association study era.Semantic proximity Read ↗

Molecular genetic models related to schizophrenia and psychotic illness: heuristics and challenges.Semantic proximity Read ↗

Constitutive genetic deletion of the growth regulator Nogo-A induces schizophrenia-related endophenotypes.Semantic proximity Read ↗

Association study of Nogo-related genes with schizophrenia in a Japanese case-control sample.Semantic proximity Read ↗

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.