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Article

Impact of EXO1 polymorphism in susceptibility to colorectal cancer.

Genetic testing and molecular biomarkers - 1 Oct 2010

Haghighi Mahdi Montazer, Taleghani Mohammad Yaghoob, Mohebbi Seyed Reza, Vahedi Mohsen, Fatemi Seyed Reza, Zali Narges, Shemirani Atena Irani, Zali Mohammad Reza

Abstract excerpt

BACKGROUND AND AIM: One candidate gene for colorectal cancer (CRC) susceptibility is exonuclease 1 (EXO1). It is a member of RAD2 nuclease family, which plays a major role in mismatch repair, DNA replication, and recombination. Single-nucleotide polymorphisms are shown to be related with cancer incidence. The aim of the present study was to examine the association between the L757P polymorphism at exon 13 of the...

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Source

Identifiers

PMID: 20854105
DOI: 10.1089/gtmb.2010.0034

Genes

EXO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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