Article
The relation between HLA-DRB1 alleles and the outcome of therapy in children with idiopathic thrombocytopenic purpura.
The Egyptian journal of immunology - 1 Jan 2005
El Neanaey Wafaa Ahmed, Barakat Shahira Salah, Ahmed Mohamed Abdel Rahman, El Nabie Wafaa Mohamed Hasab, Ahmed Mohamed Ebrahim Sayed
Abstract excerpt
Idiopathic thrombocytopenic purpura (ITP) is a common hematologic disease. The pathogenesis involves formation of autoantibodies against platelet glycoproteins. The mechanism of autoimmunity might involve binding of antigenic peptides to HLA antigens. In this study, we tried to find out if a specific HLA allele might be associated with the occurrence of ITP, and whether or not this specific allele, if present, is...
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