Article
High prevalence of infectious events in thrombotic thrombocytopenic purpura and genetic relationship with toll-like receptor 9 polymorphisms: experience of the French Thrombotic Microangiopathies Reference Center.
Transfusion - 1 Feb 2014
Morgand Marjolaine, Buffet Marc, Busson Marc, Loiseau Pascale, Malot Sandrine, Amokrane Kahina, Fortier Catherine, London Jonathan, Bonmarchand Guy, Wynckel Alain, Provôt François, Poullin Pascale, Vanhille Philippe, Presne Claire, Bordessoule Dominique, Girault Stéphane, Delmas Yahsou, Hamidou Mohamed, Mousson Christiane, Vigneau Cécile, Lautrette Alexandre, Pourrat Jacques, Galicier Lionel, Azoulay Elie, Pène Frédéric, Mira Jean-Paul, Rondeau Eric, Ojeda-Uribe Mario, Charron Dominique, Maury Eric, Guidet Bertrand, Veyradier Agnès, Tamouza Ryad, Coppo Paul
Abstract excerpt
BACKGROUND: Infectious events have been reported as major environmental triggers of thrombotic thrombocytopenic purpura (TTP). We detail here the potential association between infections and TTP. STUDY DESIGN AND METHODS: We recruited randomly and prospectively a cohort of 280 consecutive TTP pat...
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