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Article

Common copy number variations in fifty radiosensitive cell lines.

Genomics - 1 Feb 2012

Li Xinmin, Zhou Jian, Nahas Shareef A, Wan Haolei, Hu Hailiang, Gatti Richard A

Abstract excerpt

Hypersensitivity to radiation exposure is a major challenge to radiotherapy in the treatment of cancer patients. Copy number variations (CNVs) are believed to identify genomic regions of functional significance for radiosensitivity (RS) but have yet to be systematically investigated. We used Affymetrix 6.0 SNP arrays to survey common CNVs in a cohort of 50 radiosensitive lymphoblastoid cell lines (RS-LCLs)...

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Share to Cell Survival
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22200558
DOI: 10.1016/j.ygeno.2011.11.001

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