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Article

Mutation analysis of VCP in familial and sporadic amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Jul 2012

Williams Kelly L, Solski Jennifer A, Nicholson Garth A, Blair Ian P

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the progressive loss of motor neurons in the motor cortex, brain stem and spinal cord. Mutations in the valosin-containing protein gene (VCP) were recently described in ALS families. Some of these families included diagnoses of other clinical features including frontotemporal dementia, Paget's disease, inclusion body...

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Source

Identifiers

PMID: 22196955
DOI: 10.1016/j.neurobiolaging.2011.11.022

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mutation analysis of VCP in familial and sporadic amyotrophic lateral sclerosis.PMID 22196955Read ↗

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