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Article

Mutational analysis of the VCP gene in Parkinson's disease.

Neurobiology of aging - 1 Jan 2012

Majounie Elisa, Traynor Bryan J, Chiò Adriano, Restagno Gabriella, Mandrioli Jessica, Benatar Michael, Taylor J Paul, Singleton Andrew B

Abstract excerpt

Mutations in the valosin-containing protein gene (VCP) have been identified in neurological disorders (inclusion body myopathy--early Paget's disease of the bone--frontotemporal dementia and amyotrophic lateral sclerosis) and are thought to play a role in the clearance of abnormally folded proteins. Parkinsonism has been noted in kindreds with VCP mutations. Based on this, we hypothesized that mutations in VCP...

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Source

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Identifiers

PMID: 21920633
DOI: 10.1016/j.neurobiolaging.2011.07.011
PMCID: PMC3221929

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutational analysis of the VCP gene in Parkinson's disease.PMID 21920633Read ↗

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