Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation analysis of VCP in British familial and sporadic amyotrophic lateral sclerosis patients.

Neurobiology of aging - 1 Nov 2012

Miller Jack W, Smith Bradley N, Topp Simon D, Al-Chalabi Ammar, Shaw Christopher E, Vance Caroline

Abstract excerpt

Mutations in the valosin-containing-protein (VCP) gene are associated with the multidisorder disease, inclusion body myopathy with Pagets and associated frontotemporal dementia. This disease is characterized pathologically by large ubiquitinated, TAR DNA Binding Protein 43 (TDP-43) positive inclusions. These inclusions are also a common feature in neurological diseases including amyotrophic lateral sclerosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to Dementia

Share to DNA-Binding Proteins

Share to DNA Mutational Analysis

Share to Mutation

Share to Valosin Containing Protein

Source

Identifiers

PMID: 22789697
DOI: 10.1016/j.neurobiolaging.2012.06.003

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation analysis of VCP in British familial and sporadic amyotrophic lateral sclerosis patients.PMID 22789697Read ↗

Mutation analysis of VCP in familial and sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

VCP mutations in familial and sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

Mutational analysis of VCP gene in familial amyotrophic lateral sclerosis.Semantic proximity Read ↗

Mutational analysis of the VCP gene in Parkinson's disease.Semantic proximity Read ↗

Valosin-containing protein (VCP) mutations in sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

VCP gene analyses in Japanese patients with sporadic amyotrophic lateral sclerosis identify a new mutation.Semantic proximity Read ↗

Screening of VCP mutations in Chinese amyotrophic lateral sclerosis patients.Semantic proximity Read ↗

VCP mutations are not a major cause of familial amyotrophic lateral sclerosis in the UK.Semantic proximity Read ↗

Novel mutation in VCP gene causes atypical amyotrophic lateral sclerosisSemantic proximity Read ↗

Genotype-phenotype study in patients with valosin-containing protein mutations associated with multisystem proteinopathy.Semantic proximity Read ↗

VCP-related myopathy: a case series and a review of literature.Semantic proximity Read ↗

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.