Article
Association of variants in innate immune genes with asthma and eczema.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jun 2012
Sharma Sunita, Poon Audrey, Himes Blanca E, Lasky-Su Jessica, Sordillo Joanne E, Belanger Kathleen, Milton Donald K, Bracken Michael B, Triche Elizabeth W, Leaderer Brian P, Gold Diane R, Litonjua Augusto A
Abstract excerpt
BACKGROUND: The innate immune pathway is important in the pathogenesis of asthma and eczema. However, only a few variants in these genes have been associated with either disease. We investigate the association between polymorphisms of genes in the innate immune pathway with childhood asthma and eczema. In addition, we compare individual associations with those discovered using a multivariate approach. METHODS:...
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