Article
Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG.
Acta neuropathologica communications - 23 Apr 2020
Chiang Jason, Diaz Alexander K, Makepeace Lydia, Li Xiaoyu, Han Yuanyuan, Li Yimei, Klimo Paul, Boop Frederick A, Baker Suzanne J, Gajjar Amar, Merchant Thomas E, Ellison David W, Broniscer Alberto, Patay Zoltan, Tinkle Christopher L
Abstract excerpt
Diffuse intrinsic pontine glioma (DIPG) is most commonly diagnosed based on imaging criteria, with biopsy often reserved for pontine tumors with imaging features not typical for DIPG (atypical DIPG, 'aDIPG'). The histopathologic and molecular spectra of the clinical entity aDIPG remain to be studied systematically. In this study, thirty-three patients with newly diagnosed pontine-centered tumors with imaging...
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