Article
Genetic variants in the KDR gene is associated with the prognosis of transarterial chemoembolization treated hepatocellular carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2014
Zheng You-Bing, Huang Jian-Wen, Zhan Mei-Xiao, Zhao Wei, Liu Bing, He Xu, Li Yong, Hu Bao-Shan, Lu Li-Gong
Abstract excerpt
Kinase insert domain receptor (KDR) is the principal receptor that promotes the proangiogenic action of vascular endothelial growth factor and is involved in the tumorigenesis and progression of many malignancies, including hepatocellular carcinoma (HCC). Single-nucleotide polymorphisms (SNPs) of KDR have been reported to be with the risk and prognosis of several malignancies. Our aim was to determine whether...
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