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Analysis of glutathione peroxidase 1 gene polymorphism and Keshan disease in Heilongjiang Province, China.

Genetics and molecular research : GMR - 2 Dec 2011

Wei H L, Pei J R, Jiang C X, Zhou L W, Lan T, Liu M, Wang T

Abstract excerpt

Keshan disease (KD) is an endemic cardiomyopathy associated with selenium deficiency. Recent studies indicate that glutathione peroxidase 1 (GPx1) mutation decreases GPx activity in myocardial cells and increases the risk of KD. To further clarify the correlation between GPx1 polymorphism and KD, we analyzed GPx1 polymorphism, blood selenium levels and GPx activity in KD patients and healthy controls in...

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Identifiers

PMID: 22180033
DOI: 10.4238/2011.December.2.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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