Article
[Polymorphisms in the glutathione peroxidase-1 gene associated with increased risk of Keshan disease].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Jul 2010
Lei Cong, Niu Xiao-lin, Wei Jin, Zhu Jian-hong, Zhu Yi
Abstract excerpt
OBJECTIVE: To assess the association of blood selenium and polymorphism of glutathione peroxidase-1 (GPx-1) genes in patients with Keshan Disease (KD) and provide genetic evidence for KD susceptibility. METHODS: The levels of whole blood selenium and the activity of GPx-1 were measured with spectrophotometric and enzymatic method among 71 KD patients and 290 controls (including 78 internal controls and 212...
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