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Article

Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.

Diabetes care - 1 Feb 2012

Delahanty Linda M, Pan Qing, Jablonski Kathleen A, Watson Karol E, McCaffery Jeanne M, Shuldiner Alan, Kahn Steven E, Knowler William C, Florez Jose C, Franks Paul W

Abstract excerpt

OBJECTIVE: We tested genetic associations with weight loss and weight regain in the Diabetes Prevention Program, a randomized controlled trial of weight loss-inducing interventions (lifestyle and metformin) versus placebo. RESEARCH DESIGN AND METHODS: Sixteen obesity-predisposing single nucleotide polymorphisms (SNPs) were tested for association with short-term (baseline to 6 months) and long-term (baseline to 2...

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Source

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Identifiers

PMID: 22179955
DOI: 10.2337/dc11-1328
PMCID: PMC3263869

Genes

NEGR1
PPARG
BDNF
FTO
GNPDA2
LYPLAL1
MTCH2
TMEM18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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