Article
A study to investigate genetic factors associated with weight gain in people with diabetes: analysis of polymorphisms in four relevant genes.
Adipocyte - 1 Dec 2023
Heald Adrian, Qin Rui, Loureiro Camila M, Williams Richard, Devaney Dopson Chloe, Gibson J Martin, Narayanan Ram Prakash, Fachim Helene, McCay Kevin, Ollier William
Abstract excerpt
BACKGROUND: Weight change is often seen in people with diabetes. We investigated the effects of genes associated with weight change/glucose handling/insulin-signalling. MATERIALS/METHODS: DNA from diabetes individuals and non-diabetes individuals, plus clinical data, were available from the DARE study (n = 379 individuals: T1D n = 111; T2D n = 222; controls n = 46). Weight gain was assessed by temporal change of...
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