Article
A new approach to manipulate the fate of single neural stem cells in tissue.
Nature neuroscience - 18 Dec 2011
Taverna Elena, Haffner Christiane, Pepperkok Rainer, Huttner Wieland B
Abstract excerpt
A challenge in the field of neural stem cell biology is the mechanistic dissection of single stem cell behavior in tissue. Although such behavior can be tracked by sophisticated imaging techniques, current methods of genetic manipulation do not allow researchers to change the level of a defined gene product on a truly acute time scale and are limited to very few genes at a time. To overcome these limitations, we...
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