Article
DNA microarray SNP associations with clinical efficacy and side effects of domperidone treatment for gastroparesis.
Journal of biomedical informatics - 1 Apr 2012
Wang Dairong, Parkman Henry P, Jacobs Michael R, Mishra Anurag K, Krynetskiy Evgeny, Obradovic Zoran
Abstract excerpt
BACKGROUND: Domperidone treatment for gastroparesis is associated with variable efficacy as well as the potential for side effects. DNA microarray single nucleotide polymorphism (SNP) analysis may help to elucidate the role of genetic variability on the therapeutic effectiveness and toxicity of domperidone. AIM: The aim of this study was to identify SNPs that are associated with clinical efficacy and side effects...
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