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Article

Predicting potentially functional SNPs in drug-response genes.

Pharmacogenomics - 1 Apr 2009

Pang Grace S Y, Wang Jingbo, Wang Zihua, Lee Caroline G L

Abstract excerpt

SNPs are known to contribute to variations in drug response and there are more than 14 million polymorphisms spanning the human genome. However, not all of these SNPs are functional. It would be impractical and costly to evaluate every individual SNP for functionality experimentally. Consequently, one of the major challenges for researchers has been to seek out functional SNPs from all the SNPs in the human...

Topics

Animals
Databases, Genetic
Genome, Human
Humans
Internet
Pharmaceutical Preparations
Pharmacogenetics
Polymorphism, Single Nucleotide
Predictive Value of Tests
Regulatory Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19374519
DOI: 10.2217/pgs.09.12

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