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Article

Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects.

Digestive diseases and sciences - 1 Jan 2011

Parkman Henry P, Jacobs Michael R, Mishra Anurag, Hurdle Jessica A, Sachdeva Priyanka, Gaughan John P, Krynetskiy Evgeny

Abstract excerpt

BACKGROUND: Domperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability. Effectiveness and side-effects from domperidone may be influenced by patient-related factors including polymorphisms in genes encoding drug-metabolizing enzymes, drug transporters, and domperidone targets. AIMS: The aim of this study was to determine if demographic and pharmacogenetic...

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PMID: 21063774
DOI: 10.1007/s10620-010-1472-2

Genes

ABCB1
KCNH2
DRD2
KCNQ1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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