Article
Advances in the development of genetic markers for the diagnosis of disease and drug response.
Expert review of molecular diagnostics - 1 Sept 2002
Halapi Eva, Hakonarson Hakon
Abstract excerpt
Genetic diversity, including single nucleotide polymorphisms, contributes to both disease susceptibility and variability in drug response. Since most genes contain multiple single nucleotide polymorphisms, identifying those that are most relevant with respect to disease or drug response is important and may uncover variants that are predictive of either disease susceptibility or therapeutic response to drugs,...
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