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Article

Genetic and phenotypic characterization of sylvatic dengue virus type 4 strains.

Virology - 5 Feb 2012

Rossi S L, Nasar F, Cardosa J, Mayer S V, Tesh R B, Hanley K A, Weaver S C, Vasilakis Nikos

Abstract excerpt

Four serotypes of dengue virus (DENV 1-4) currently circulate between humans and domestic/peridomestic Aedes mosquitoes, resulting in 100 million infections per year. All four serotypes emerged, independently, from sylvatic progenitors transmitted among non-human primates by arboreal Aedes mosquitoes. This study investigated the genetic and phenotypic changes associated with emergence of human DENV-4 from its...

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Identifiers

PMID: 22178263
DOI: 10.1016/j.virol.2011.11.018
PMCID: PMC3253985

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