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A laboratory-adapted and a clinical isolate of dengue virus serotype 4 differently impact Aedes aegypti life-history traits relevant to vectorial capacity.

Microbiology spectrum - 2 Dec 2025

Maraschin Mariana, Novak Diego, Klein Junior Valdorion José, Granella Lucilene W, Hubner Luiza J, Medeiros Athina R, Gräf Tiago, Toledo-Silva Guilherme, Mansur Daniel S, Oliveira José Henrique M

Abstract excerpt

Dengue virus cases are on the rise globally, and strategies to control its primary vector, the mosquito Aedes aegypti, represent a promising approach. However, the interaction between virus serotypes and genotypes with Ae. aegypti is poorly characterized in terms of life-history traits related to vector capacity and mosquito disease tolerance. Here, we infected Ae. aegypti with two phylogenetically distant...

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Identifiers

PMID: 41147853
DOI: 10.1128/spectrum.00001-25
PMCID: PMC12671126

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