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Evolutionary Relationships of Endemic/Epidemic and Sylvatic Dengue Viruses

1 Apr 2000

Abstract excerpt

Endemic/epidemic dengue viruses (DEN) that are transmitted among humans by the mosquito vectors Aedes aegypti and Aedes albopictus are hypothesized to have evolved from sylvatic DEN strains that are transmitted among nonhuman primates in West Africa and Malaysia by other Aedes mosquitoes. We tested this hypothesis with phylogenetic studies using envelope protein gene sequences of both endemic/epidemic and...

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PMID: 10708439
DOI: 10.1128/jvi.74.7.3227-3234.2000

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