Article
Polymorphisms in the serotonin transporter protein (SERT) gene in patients with pulmonary arterial hypertension.
Archivos de bronconeumologia - 1 Mar 2012
Baloira Adolfo, Núñez Marta, Cifrian José, Vilariño Carlos, Ojeda María, Valverde Diana
Abstract excerpt
UNLABELLED: Serotonin is a potent vasoconstrictor and pulmonary vascular growth factor whose concentration is increased in patients with pulmonary arterial hypertension (PAH). Its functions are mediated in part by the serotonin transporter protein (SERT) whose gene can have two allelic forms, both long (L) and short (S). The first was associated with greater function. OBJECTIVES: To determine whether the...
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