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Article

Genetic association of the serotonin transporter in pulmonary arterial hypertension.

American journal of respiratory and critical care medicine - 1 Apr 2006

Machado Rajiv D, Koehler Rolf, Glissmeyer Eric, Veal Colin, Suntharalingam Jay, Kim Miryoung, Carlquist John, Town Margaret, Elliott C Gregory, Hoeper Marius, Fijalkowska Anna, Kurzyna Marcin, Thomson Jennifer R, Gibbs Simon R, Wilkins Martin R, Seeger Werner, Morrell Nicholas W, Gruenig Ekkehard, Trembath Richard C, Janssen Bart

Abstract excerpt

RATIONALE: The bone morphogenetic receptor type II gene is the major genetic determinant for the inherited form of pulmonary arterial hypertension. However, deleterious mutations of this gene are not observed in the majority of subjects who develop the condition spontaneously and familial disease displays age- and sex-dependent penetrance, indicating the requirement for additional environmental and/or genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16399993
DOI: 10.1164/rccm.200509-1365OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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