Article
DNA repair gene excision repair cross complementing-group 1 (ERCC1) in head and neck squamous cell carcinoma: analysis of methylation and polymorphism (G19007A), protein expression and association with epidemiological and clinicopathological factors.
Histopathology - 1 Feb 2012
Lima Lucianne Maia Costa, de Souza Ludmilla Regina, da Silva Thiago Fonseca, Pereira Camila Santos, Guimarães André Luiz Sena, de Paula Alfredo Maurício Batista, de Andrade Carvalho Heloisa
Abstract excerpt
AIMS: To evaluate the associations of excision repair cross complementing-group 1 (ERCC1) (DNA repair protein) (G19007A) polymorphism, methylation and immunohistochemical expression with epidemiological and clinicopathological factors and with overall survival in head and neck squamous cell carcinoma (HNSCC) patients. METHODS AND RESULTS: The study group comprised 84 patients with HNSCC who underwent surgery and...
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